Co-reporter: Zhenbo Yuan, Weiwei Wei, Aijun Lin, and Hequan Yao
pp: 3370-3373
Publication Date(Web):July 5, 2016
DOI: 10.1021/acs.orglett.6b01512
A novel [3 + 2] annulation between para-quinone methides and vinylcyclopropanes for the synthesis of spiro[4.5]deca-6,9-diene-8-ones has been described. The palladium and phosphine–thiourea cooperative catalysis system played an important role in high yields and diastereoselectivities. The reaction exhibited good functional group tolerance and scalability.
