The separation and reuse of nanocatalysts remains a major challenge. Herein, we report a novel approach to prepare palladium nanowire array catalysts by reducting PdCl2 in the pores of anodic aluminum oxide (AAO) templates with backside Al sheets via a hydrothermal process. Suzuki coupling reactions and 4-nitrophenol (4-NP) reduction reactions were employed to study the catalytic activity of the nanocatalysts. The nanocatalysts demonstrated good activity, great thermal stability, easy separation, and excellent reusability in both Suzuki reaction and 4-NP reduction.Keywords: AAO; heterogeneous catalysts; high temperature stability; nanoarray; Pd; Suzuki reaction;