Martina Lahmann

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Organization: Bangor University
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Co-reporter:Yulong Shan, Farah Oulaidi, Martina Lahmann
Tetrahedron Letters 2013 Volume 54(Issue 30) pp:3960-3961
Publication Date(Web):24 July 2013
DOI:10.1016/j.tetlet.2013.05.086
The Heyns rearrangement is possibly one of the oldest, easiest and most economic ways to synthesise 2-deoxy-2-amino sugars. Initially reported yields were disappointingly low, but in the late 90s Wrodnigg and Stütz discovered modified reaction conditions that gave substantially increased yields, making the reaction viable on preparative scale. Requiring larger amounts of N-acetyl lactosamine, we utilised the reported reaction conditions and found that additional modifications, especially in the work-up procedure—for example employing rapid filtration of crude diethyl ether precipitates, were necessary to make this approach robust in the research laboratory environment.
Co-reporter:Viviane Fournière, Linnéa Skantz, Ferenc Sajtos, Stefan Oscarson, Martina Lahmann
Tetrahedron 2010 66(39) pp: 7850-7855
Publication Date(Web):
DOI:10.1016/j.tet.2010.07.036
Histiopterosin A
(10S,11S)-Pterosin
Pteroside K
(3R)-Pterosin D
(2S)-6-(2-hydroxyethyl)-5-(hydroxymethyl)-2,7-dimethyl-2,3-dihydro-1H-inden-1-one
[(2R)-2,4,6-trimethyl-3-oxo-2,3-dihydro-1H-inden-5-yl]acetic acid
(2S)-pterosin K
(2R,3S)-Pterosin J
2-(2,2,4,6-tetramethyl-3-oxo-2,3-dihydro-1H-inden-5-yl)ethyl beta-D-allopyranoside
(2R,3R)-3-hydroxy-6-(2-hydroxyethyl)-2,5,7-trimethyl-2,3-dihydro-1H-inden-1-one