Co-reporter:Wen-Hao Zhang, Chao-Xia Sui, Xie Wang, Gong-Ju Yin, Ying-Fan Liu and Ding Zhang
Analyst 2014 vol. 139(Issue 24) pp:6357-6360
Publication Date(Web):10 Oct 2014
DOI:10.1039/C4AN01698J
CdTe nanocrystals capped by cysteamine were synthesized to study Cr(V)-induced genotoxicity. On the surface of TiO2 thin films, the stepwise process of DNA breakage induced by Cr(V)–GSH complexes was vividly observed by using CdTe–DNA self-assembled fluorescent probes; in acetate buffer solution, an analytical method was developed to detect Cr(V)-induced genotoxicity with CdTe fluorescent probes.
Co-reporter:Ying-Fan Liu, Lei Wang, Wan-Zhen Shi, Yan-Hui Zhang and Shao-Ming Fang
RSC Advances 2014 vol. 4(Issue 95) pp:53142-53148
Publication Date(Web):25 Sep 2014
DOI:10.1039/C4RA08360A
This study focused on the synthesis of novel chiral Ag2S and Ag2S–Zn nanocrystals (NCs) with chiral Pen as a capping reagent in an aqueous solution. Luminescence studies indicated that all the prepared Ag2S and Ag2S–Zn NCs exhibited size-tunable photoluminescence (PL) emission at 500–700 nm. Compared with Ag2S, the PL emission of the Ag2S–Zn NCs could improve by around 2.4-fold. XRD peaks of the as-prepared Ag2S NCs were weak, whereas the XRD peaks of the Ag2S–Zn NCs had the characteristics of a monoclinic crystal structure. The circular dichroism (CD) test showed that the prepared NCs revealed a clear mirror-image relationship in their CD signals at 300–700 nm, and Zn2+ played a key role in the Cotton effect of the NCs. The chiral and fluorescent properties of these NCs are likely to find widespread applications in bioimaging, chemical and biosensing, and possibly in asymmetry catalysis.
Co-reporter:Ying-Fan Liu, Guo-Qing Wang, Jian-Bo Zhao, Ling Jiang, Shao-Ming Fang, Yu-An Sun
Colloids and Surfaces A: Physicochemical and Engineering Aspects 2013 Volume 426() pp:12-17
Publication Date(Web):5 June 2013
DOI:10.1016/j.colsurfa.2013.02.038
We report a route of synthesizing water-soluble chiral luminescent Ag nanoclusters (NCs) using d-penicillium and l-penicillium as stabilizer agents by photo-reduction method. These Ag NCs exhibit characteristic of tunable fluorescence from 603 nm to 640 nm, controllable Cotton effects or circular dichroism (CD) signals with an opposite sign (mirror–image relationship) in metal-based electronic transition regions by varying irradiating time and are stable under ambient conditions. The hemolysis results show that the prepared Ag NCs are better biocompatibility compared with that of CdTe quantum dots (QDs). The stability, chirality, biocompatibility and fluorescent properties of these Ag NCs are likely to find widespread applications in bioimaging, chemical and biosensing, and also possibly in asymmetry catalysis.Graphical abstractFluorescence spectra of the Ag nanocluster after different periods of UV irradiation: 1) 20, 2) 30, 3) 40, 4) 50, and 5) 70 min.Highlights► The Ag NCs are prepared using chiral penicillium as ligand and UV light to reduce a silver salt. ► The Ag NCs exhibit defined emission wavelength and controllable chirality by varying irradiating time. ► The hemolysis results show that the Ag NCs are better biocompatibility compared with that of CdTe QDs.
Co-reporter:Ying-Fan Liu;Bing Xie;Zhi-Gang Yin;Shao-Ming Fang ;Jian-Bo Zhao
European Journal of Inorganic Chemistry 2010 Volume 2010( Issue 10) pp:1501-1506
Publication Date(Web):
DOI:10.1002/ejic.200900978
Abstract
Thioglycolic acid (TGA) is a popular coating material for the preparation of aqueous quantum dots (QDs), yet dihydrolipoic acid (DHLA) has not been studied much. Here we present a detailed study on the aqueous synthesis of CdTe/CdS quantum dots with a DHLA coating. The outer CdS shell and DHLA stabilizer provide efficient confinement of electron and hole wave functions inside the nanocrystal as well as high photochemical stability. At the optimum ratios and reaction conditions, the results indicate that the DHLA-capped CdTe/CdS QDs exhibit high fluorescence quantum yields (QYs) of about 48 % over a spectral range of 551–571 nm, and the best QY is 87 %. These DHLA-capped core–shell QDs are highly biocompatible and monodisperse. In particular, they have exhibited excellent colloidal and photostability over one year of study. The synthesis of QDs by using DHLA as stabilizer is simple and environmentally friendly, and it can easily be extended to the large-scale, aqueous-phase production of QDs. At a QD dose of 120 μg/mL, TGA-stabilized CdTe QDs induce 9.5 % hemolysis, whereas DHLA-stabilized CdTe/CdS QDs induce only 3 % hemolysis. Hemolytic results indicate that DHLA-stabilized QDs are more biocompatible than TGA-capped CdTe QDs, which is especially important for QDs as biomarkers in biological detection and diagnosis.
